Structure of PDB 7oro Chain A Binding Site BS02 |
| >7oro Chain A (length=2008)
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MDYQEYQQFLARINTARDACVAKDIDVDLLMARKDYFGRELCKSLNIEYR
NDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNE
SSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYP
TIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPE
FWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKD
YSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHD
QKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKM
MDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFM
INNDLIDKSEKLKLFKNFCGIGKHVSKPKILDFDDANMYLASLTMMEQSK
KILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFS
TLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSAKATVVYSIIVLHKE
EENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLL
FKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVK
DYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDIT
QKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLA
KTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHL
RNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKEYEMLRNAMPNYTD
YISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTS
KDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKS
EQEIRFLVETTRQKNREIDEAIEIEKLSLGKAKGLKMEINADMSKWSAQD
VFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKV
AYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILK
EAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACL
TFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGP
YEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPI
DYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVM
QKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGET
SDMRGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKP
ELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPV
IDFSGIRDKYINLGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILND
PMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYS
KNNPDIQGADPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDI
VFELKEMTRFYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIK
DKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDS
LSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQA
DLDKYDAMKILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFE
GPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNIND
GLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERET
KIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICL
IKNGMDHMYHSFDVPKCFINWVMFREFINSLPGTDIPPWNVMTENFKKKC
IALINSKF |
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| PDB | 7oro Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. |
| Resolution | 2.9 Å |
Binding residue
(original residue number in PDB) | H312 N313 N318 K368 R372 Q377 I378 K381 K382 L383 W395 E396 Q397 L471 K472 N517 S520 V521 Y524 R526 H527 R531 M534 C535 A536 N537 N538 N1308 I1511 L1512 H1515 K1516 |
Binding residue
(residue number reindexed from 1) | H312 N313 N318 K368 R372 Q377 I378 K381 K382 L383 W395 E396 Q397 L459 K460 N505 S508 V509 Y512 R514 H515 R519 M522 C523 A524 N525 N526 N1240 I1443 L1444 H1447 K1448 |
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