Structure of PDB 7orl Chain A Binding Site BS02 |
| >7orl Chain A (length=2183) Species: 11577 (La Crosse virus)
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MDYQEYQQFLARINTARDACVAKDIDVDLLMARKDYFGRELCKSLNIEYR
NDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNE
SSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYP
TIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPE
FWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKD
YSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHD
QKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKM
MDIGDKAIEYEEFCMSLKSKKKLEPKQINNALVLWEQQFMINNDLIDKSE
KLKLFKNFCGIGKHKQFKNKMLEDLEVSKPKILDFDDANMYLASLTMMEQ
SKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISD
FSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSADIKTKKATVVYS
IIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGL
FLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSL
AISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIY
LSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKH
HVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLAD
TSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQKMRL
ANPMFVTDEQVCLEVGHCNYEMLRNAMPNYTDYISTKVFDRLYELLDKKV
LTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYA
VERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREI
DEAIEALALGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALD
PILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTN
QLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILV
NSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTY
VTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQ
TAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIP
IELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAE
VKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPR
KFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKD
YMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKEKE
PDILGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANT
HILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDIQGA
DPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTR
FYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHY
LKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQL
IIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMK
SHERVTWNDWQTSRHLDMGSINLTITGYNRSITIIGEDNKLTYAELCLTR
KTPENITISGRKLLGSRHGLKFENMSKIQTYPGNYYITYRKKDRHQFVYQ
IHSHESITRRNEEHMAIIYNEITPVCVVNVAEVDGDQRILIRSLDYLNND
IFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLL
NLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHST
PIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLG
CLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPINWVMF
REFINSLPGTDIPPWNVMTENFKKKCIALINSK |
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| PDB | 7orl Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. |
| Resolution | 3.6 Å |
Binding residue
(original residue number in PDB) | Q291 R292 K302 C419 G420 I421 G422 H424 Q426 F427 L435 K439 P440 A548 R592 A593 R595 R600 T642 K643 Y677 K679 H760 H761 V764 K768 H890 L1113 Q1116 V1118 Y1120 D1123 |
Binding residue
(residue number reindexed from 1) | Q291 R292 K302 C409 G410 I411 G412 H414 Q416 F417 L425 K429 P430 A538 R582 A583 R585 R590 T632 K633 Y667 K669 H750 H751 V754 K758 H867 L1083 Q1086 V1088 Y1090 D1093 |
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