Structure of PDB 7ork Chain A Binding Site BS02 |
| >7ork Chain A (length=2182) Species: 11577 (La Crosse virus)
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MDYQEYQQFLARINTARDACVAKDIDVDLLMARKDYFGRELCKSLNIEYR
NDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNE
SSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYP
TIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPE
FWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKD
YSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHD
QKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKM
MDIGDKAIEYEEFCMSLKSKALEPKQINNALVLWEQQFMINNDLIDKSEK
LKLFKNFCGIGKHKQFKNKMLEDLEVSKPKILDFDDANMYLASLTMMEQS
KKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDF
STLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSADIKTKKATVVYSI
IVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLF
LTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLA
ISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYL
SDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHH
VMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADT
SRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELRKMRLA
NPMFVTDEQVCLEVGHCNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVL
TDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAV
ERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREID
EAIEALATLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALD
PILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTN
QLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILV
NSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTY
VTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQ
TAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIP
IELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAE
VKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPR
KFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKD
YMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKKEP
DILGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTH
ILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDIQGAD
PTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRF
YQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYL
KQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLI
IDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKS
HERVTWNDWQTSRHLDMGSINLTITGYNRSITIIGEDNKLTYAELCLTRK
TPENITISGRKLLGSRHGLKFENMSKIQTYPGNYYITYRKKDRHQFVYQI
HSHESITRRNEEHMAIIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDI
FSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLN
LNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTP
IFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGC
LEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPINWVMFR
EFINSLPGTDIPPWNVMTENFKKKCIALINSK |
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| PDB | 7ork Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. |
| Resolution | 3.1 Å |
Binding residue
(original residue number in PDB) | H527 N528 D549 K551 T552 K553 K598 K841 S842 F948 K950 I960 F961 K968 R976 K979 M989 I990 S991 G1146 Y1150 F1432 T1434 I1500 N1502 P1503 Q1505 E1509 K1516 D1542 |
Binding residue
(residue number reindexed from 1) | H516 N517 D538 K540 T541 K542 K587 K830 S831 F924 K926 I936 F937 K944 R952 K955 M965 I966 S967 G1116 Y1120 F1402 T1404 I1470 N1472 P1473 Q1475 E1479 K1486 D1501 |
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