Structure of PDB 7orj Chain A Binding Site BS02 |
| >7orj Chain A (length=2129) Species: 11577 (La Crosse virus)
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MDYQEYQQFLARINTARDACVAKDIDVDLLMARKDYFGRELCKSLNIEYR
NDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNE
SSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYP
TIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPE
FWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKD
YSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHD
QKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKM
MDIGDKAIEYEEFCMSLKSKALEPKQINNALVLWEQQFMINNDLIDKSEK
LKLFKNFCGIGKHVSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKP
DNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQ
YNRHNTFRIAMCANNNVFAIVFPSADIKTKKATVVYSIIVLHKEEENIFN
PGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNP
TLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEK
FSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKD
NRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEI
ECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIEN
RNNFRRSITTISTFTSSKSCLKIGDFRKEMLRNAMPNYTDYISTKVFDRL
YELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEY
EAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVET
TRQKNREIDEAIEALATLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFY
KYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQ
NDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAI
TLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFG
CQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYED
LASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYF
PAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKR
ESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDM
RGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELL
VTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDF
SGIRDKKEPDILGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDP
MMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSK
NNPDIQGADPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIV
FELKEMTRFYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKD
KEWYTVHYLKQILSSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDE
FSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHER
VTWNDWQTSRHLDMGSINLTITGYNRSITIIGEDNKLTYAELCLTRKTPE
NITISGRKLLGSRHGLKFENMSKIQTYPGNYYITYRKKDRHQFVYQIHSH
ESITRRNEEHMAIIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSL
SRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNY
DNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFN
IYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEA
VVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPINWVMFREFI
NSLPGTDIPPWNVMTENFKKKCIALINSK |
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| PDB | 7orj Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. |
| Resolution | 3.9 Å |
Binding residue
(original residue number in PDB) | H527 A548 D549 K551 T552 K553 K598 K759 T836 K841 S842 F948 I960 R976 M989 I990 S991 G1146 Y1150 F1432 T1434 I1500 N1502 Q1505 E1509 F1513 D1542 |
Binding residue
(residue number reindexed from 1) | H504 A525 D526 K528 T529 K530 K575 K736 T813 K818 S819 F883 I895 R911 M924 I925 S926 G1075 Y1079 F1361 T1363 I1429 N1431 Q1434 E1438 F1442 D1460 |
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