Structure of PDB 7obe Chain A Binding Site BS02

Receptor Information
>7obe Chain A (length=480) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NENSDVSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRA
FAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDF
QQVKRLSPNDPDATRKLKECEKAVMKLKFEEAISVPVSERRSVAESIDFH
TIEVEPQYSGARIEGEEVTLDFVKTMMEDFKNQKTLHKRYAYQIVLQTRQ
ILLALPSLVDISVPHGKHITVCGDVHGQFYDLLNIFELNGLPSEENPYLF
NGDFVDRGSFSVEIILTLFAFKCMCPSSIYLARGNHESKSMNKIYGFEGE
VRSKLSEKFVDLFAEVFCYLPLAHVINGKVFVVHGGLFSVDGVKLSDIRA
IDRFCEPPEEGLMCELLWSDPQPLPGRGPSKRGVGLSFGGDVTKRFLQDN
NLDLLVRSHEVKDEGYEVEHDGKLITVFSAPNYCDQMGNKGAFIRFEAPD
MKPNIVTFSAVPHPDVKPMAYANNFLRMFN
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7obe Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7obe Conformational Change of Tetratricopeptide Repeats Region Triggers Activation of Phytochrome-Associated Protein Phosphatase 5.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D257 N289 H338 H413
Binding residue
(residue number reindexed from 1)		D253 N285 H334 H409
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0017018 myosin phosphatase activity
GO:0046872 metal ion binding
GO:0046906 tetrapyrrole binding
Biological Process
GO:0006913 nucleocytoplasmic transport
GO:0010017 red or far-red light signaling pathway
GO:0010019 chloroplast-nucleus signaling pathway
GO:1902325 negative regulation of chlorophyll biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0009506 plasmodesma
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0031965 nuclear membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7obe, PDBe:7obe, PDBj:7obe
PDBsum7obe
PubMed34721460
UniProtQ84XU2|PPP5_ARATH Serine/threonine-protein phosphatase 5 (Gene Name=PAPP5)

[Back to BioLiP]