Structure of PDB 7n7g Chain A Binding Site BS02

Receptor Information
>7n7g Chain A (length=138) Species: 1352 (Enterococcus faecium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIKGINHITYSVSNIAKSIEFYRDILGADILVESETLAYFNLGGIWLALN
EEKNIPRSEIKYSYTHIAFTISDNDFEDWYNWLKENEVNILEGRDRDIRD
KKSIYFTDLDGHKLELHTGSLEDRLSYYKEAKPHMNFY
Ligand information
Ligand IDFCN
InChIInChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1
InChIKeyYMDXZJFXQJVXBF-STHAYSLISA-N
SMILES
SoftwareSMILES
CACTVS 3.341C[C@@H]1O[C@@H]1[P](O)(O)=O
OpenEye OEToolkits 1.5.0C[C@H]1[C@H](O1)P(=O)(O)O
ACDLabs 10.04O=P(O)(O)C1OC1C
OpenEye OEToolkits 1.5.0CC1C(O1)P(=O)(O)O
CACTVS 3.341C[CH]1O[CH]1[P](O)(O)=O
FormulaC3 H7 O4 P
NameFOSFOMYCIN;
1,2-EPOXYPROPYLPHOSPHONIC ACID
ChEMBLCHEMBL1757
DrugBankDB00828
ZINCZINC000001530427
PDB chain7n7g Chain A Residue 207 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7n7g Structural and functional characterization of fosfomycin resistance conferred by FosB from Enterococcus faecium.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Y64 H66 R94 Y105 E115 R124
Binding residue
(residue number reindexed from 1)		Y64 H66 R94 Y105 E115 R124
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n7g, PDBe:7n7g, PDBj:7n7g
PDBsum7n7g
PubMed34882867
UniProtF1C939

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