Structure of PDB 7n4p Chain A Binding Site BS02

Receptor Information
>7n4p Chain A (length=207) Species: 28377 (Anolis carolinensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNRLPYFINYFFDTYLLINEDTPVGSSVTQLLARDLDNDPLVFGVVGEEA
SRFFAVESMTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIKGSVNIQVGD
VNDNAPRFHNQPYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSFQPS
SNFFTIDSGRGIVSVIRALDYEVTQAYQLQVNATDQDKTKPLSTLANLAI
TITDVQD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7n4p Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7n4p Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation.
Resolution2.097 Å
Binding residue
(original residue number in PDB)		E19 E71 D99 V100 D102 D135
Binding residue
(residue number reindexed from 1)		E20 E72 D100 V101 D103 D136
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n4p, PDBe:7n4p, PDBj:7n4p
PDBsum7n4p
PubMed36911992
UniProtR4GAX0

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