Structure of PDB 7m41 Chain A Binding Site BS02

Receptor Information

>7m41 Chain A (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTD
ERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDE
KFNLKLVIK

Ligand information

InChI=1S/Ca/q+2

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Ca

Name

CALCIUM ION

PDB chain

7m41 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7m41 Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3).
Resolution	1.79 Å
Binding residue (original residue number in PDB)	I93 I96 M97 N98 D99
Binding residue (residue number reindexed from 1)	I93 I96 M97 N98 D99
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:7m41, PDBe:7m41, PDBj:7m41
PDBsum	7m41
PubMed	34597046
UniProt	Q8TDQ0\|HAVR2_HUMAN Hepatitis A virus cellular receptor 2 (Gene Name=HAVCR2)

[Back to BioLiP]