Structure of PDB 7m10 Chain A Binding Site BS02

Receptor Information
>7m10 Chain A (length=68) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPN
CEKTHGKSTLKKKRTWHK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7m10 Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7m10 Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Resolution1.15 Å
Binding residue
(original residue number in PDB)		C23 C26 C50 C53
Binding residue
(residue number reindexed from 1)		C21 C24 C48 C51
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:7m10, PDBe:7m10, PDBj:7m10
PDBsum7m10
PubMed33969871
UniProtO75151|PHF2_HUMAN Lysine-specific demethylase PHF2 (Gene Name=PHF2)

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