Structure of PDB 7lrf Chain A Binding Site BS02

Receptor Information
>7lrf Chain A (length=418) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQ
VRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLS
LGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNK
PSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPV
LQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKC
NGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANE
CVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGF
YRDLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRC
AKGYQQSRSPIAPCIKIP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7lrf Chain A Residue 505 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lrf The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Resolution3.21 Å
Binding residue
(original residue number in PDB)		F109 D112 N114 T120 S279 D280
Binding residue
(residue number reindexed from 1)		F70 D73 N75 T81 S240 D241
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7lrf, PDBe:7lrf, PDBj:7lrf
PDBsum7lrf
PubMed36869049
UniProtQ90922|NET1_CHICK Netrin-1 (Gene Name=NTN1)

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