Structure of PDB 7lp2 Chain A Binding Site BS02
Receptor Information
>7lp2 Chain A (length=33) Species:
9606
(Homo sapiens) [
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GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIM
Ligand information
>7lp2 Chain F (length=15) Species:
9606
(Homo sapiens) [
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MEHRGPPPEYPFKGM
Receptor-Ligand Complex Structure
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PDB
7lp2
Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release.
Resolution
1.88 Å
Binding residue
(original residue number in PDB)
K398 R400 W413
Binding residue
(residue number reindexed from 1)
K13 R15 W28
Enzymatic activity
Enzyme Commision number
2.3.2.26
: HECT-type E3 ubiquitin transferase.
2.3.2.36
: RING-type E3 ubiquitin transferase (cysteine targeting).
External links
PDB
RCSB:7lp2
,
PDBe:7lp2
,
PDBj:7lp2
PDBsum
7lp2
PubMed
34284061
UniProt
Q96PU5
|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like (Gene Name=NEDD4L)
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