Structure of PDB 7lo5 Chain A Binding Site BS02

Receptor Information
>7lo5 Chain A (length=1016) Species: 980427 (Deinococcus wulumuqiensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLQLVKKFQKRLEDIVAYGGTRNESSVRAAFQQLLSDWAEGSGLRLITEV
TQKAVAGNNVRPDGTLKDSLQQSRGYWESKDEADTLDDEIQKKLAKGYPR
DNIIFEDSRLAVLMQNGEEVQRVDMGDAGALAGLLKLFFEFEPPQVLEFR
KAVDHFKDEMPHLLKILREAADAAEQKADYRGERDHFVEIAKEAINPDFS
PRDAREMLIQHILTGDLFTSVFDNAQYHEDNNIAQQLQQLAATFYKGPVK
RDIAERTKRYYGAIQAAAAQIADHHEKQRFLKALYENFYRAYNPAGAERL
GIFYTPGEIVRFMIEATDTLLEKHFQKELADKGVEILDPATGTGTFITEL
IDFLPKAKLEQKYREELHCNELALLPYYIANLNIEATYAQKMGRYEEFRN
IVLVDTLDNTGFSGLFGSVTAENLERAKRQNARPVRVIIGNPPYRANQAN
ENDNNKNREYKEIDRRIKATYVAASTAQKTKLYDMYSRFLRWATDRLKED
GIVAFVSNSSFIDSRTFDGFRKEVVKDFDHIYILDMKGNANTSGERRKRE
GGNVFNDQIKVGVAVYFLVRSAKDTKIWYHAVPDFWRAREKLEWLKTTKF
EDIEFDHIRPDAKHNWLGQVDEENDWNEFLPVADKDTKQAKGLGQERAIF
KLYSLGVVTNRDEWVYSRAEDELADKVRYFIGRYNEIIKLPLGDLMSRNW
EGDIKMTRATIADAQSRKSYSLEKNSIVPSLYRPFDVLKMYFSKNLNEMQ
YQMPSIFPKGVGENVVIALSGSPAAKPFQVLATDILPSLDLLEKTQCLPF
YRYTMNGERLNNITDYALKAFQTHYADTSISREDIFHYVYAVLHHPAYRE
KYALNLRQEFPRIPFYPEFGRWAAWGRELMALHIGFESVAPYPLKRTDEP
PKNDTPEALALAKKARLKVQRDAAKQPTGAVELDGLTTLAGIPAAAWAYK
LGNRSALEWVLERHKETTPKDATIREKFNTYRFADHKERVIDLLARVTTV
SVETVRIVGEMPAETM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lo5 Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		N454 Q455 N457 E458 K463 Q485 K486 T487 Y490 A547 N548 R554 K567 R600 K651 V671 N673 D675 R721 R746 D803
Binding residue
(residue number reindexed from 1)		N447 Q448 N450 E451 K456 Q478 K479 T480 Y483 A540 N541 R547 K560 R587 K638 V658 N660 D662 R708 R733 D790
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7lo5, PDBe:7lo5, PDBj:7lo5
PDBsum7lo5
PubMed33826880
UniProtA0A345IJ72

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