Structure of PDB 7ljx Chain A Binding Site BS02

Receptor Information
>7ljx Chain A (length=104) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAAGFSYTD
ANQNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKGERADLIAYLKK
ATNE
Ligand information
Ligand IDFC6
InChIInChI=1S/6CN.Fe/c6*1-2;
InChIKeyHCMVSLMENOCDCK-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(#N)[Fe](C#N)(C#N)(C#N)(C#N)C#N
ACDLabs 10.04
CACTVS 3.341		N#C[Fe](C#N)(C#N)(C#N)(C#N)C#N
FormulaC6 Fe N6
NameHEXACYANOFERRATE(3-);
FERRI(III)HEXACYANIDE
ChEMBL
DrugBank
ZINC
PDB chain7ljx Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ljx Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis.
Resolution1.31 Å
Binding residue
(original residue number in PDB)		K87 K88 G89
Binding residue
(residue number reindexed from 1)		K87 K88 G89
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0009055 electron transfer activity
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0002931 response to ischemia
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
GO:0006915 apoptotic process
GO:0006979 response to oxidative stress
GO:0009629 response to gravity
GO:0010730 negative regulation of hydrogen peroxide biosynthetic process
GO:0034349 glial cell apoptotic process
GO:0034465 response to carbon monoxide
GO:0042743 hydrogen peroxide metabolic process
GO:0046688 response to copper ion
GO:1901857 positive regulation of cellular respiration
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0043293 apoptosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ljx, PDBe:7ljx, PDBj:7ljx
PDBsum7ljx
PubMed33916826
UniProtP62898|CYC_RAT Cytochrome c, somatic (Gene Name=Cycs)

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