Structure of PDB 7lc3 Chain A Binding Site BS02

Receptor Information
>7lc3 Chain A (length=557) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFRAL
GVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWD
LALNTAVSFVTNTNWRSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFA
LIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLP
YQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTAL
TNFVQMLAIFLIPTALCFAFGEVMGDRRQGRMLLWAMSVIFVICVGVVMW
AEVQGNPHLLALGTDSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAM
HDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPV
MAIAGSLVSKKSQAASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALG
PVAEYLS
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain7lc3 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7lc3 Structural basis for potassium transport in prokaryotes by KdpFABC.
Resolution3.23 Å
Binding residue
(original residue number in PDB)		R116 G232 N239 G345 G468
Binding residue
(residue number reindexed from 1)		R116 G232 N239 G345 G468
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008556 P-type potassium transmembrane transporter activity
GO:0030955 potassium ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0031004 potassium ion-transporting ATPase complex
GO:1903103 potassium:proton antiporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7lc3, PDBe:7lc3, PDBj:7lc3
PDBsum7lc3
PubMed34272288
UniProtP03959|KDPA_ECOLI Potassium-transporting ATPase potassium-binding subunit (Gene Name=kdpA)

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