Structure of PDB 7l4m Chain A Binding Site BS02

Receptor Information
>7l4m Chain A (length=350) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIRLPNPMIGFGVPNEPGLITHRSLPELARGPPFFYYENVALTPKGVWET
ISRHLFEIPPEFVDSKYFCVAARKRGYIHNLPINNRFQIQPPPKYTIHDA
FPLSKRWWPEWDKRTKLNCILTCTGSAQLTNRIRVALEPYNEEPEPPKHV
QRYVIDQCKKWNLVWVGKNKAAPLEPDEMESILGFPKNHTRGGGMSRTER
FKSLGNSFQVDTVAYHLSVLKPIFPHGINVLSLFTGIGGGEVALHRLQIK
MKLVVSVEISKVNRNILKDFWEQTNQTGELIEFSDIQHLTNDTIEGLMEK
YGGFDLVIGGSPCNNLAGGNRVSRVGLEGDQSSLFFEYCRILEVVRARMR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l4m Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Resolution2.805 Å
Binding residue
(original residue number in PDB)		E312 V314 L316 R347 R349 L395 T396 C397 R426 G479 N480 S481 S585 P586 C587 N588 G592 G593 R595 V596
Binding residue
(residue number reindexed from 1)		E38 V40 L42 R73 R75 L121 T122 C123 R152 G205 N206 S207 S311 P312 C313 N314 G318 G319 R321 V322
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7l4m, PDBe:7l4m, PDBj:7l4m
PDBsum7l4m
PubMed34078593
UniProtQ9M548|DRM2_ARATH DNA (cytosine-5)-methyltransferase DRM2 (Gene Name=DRM2)

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