Structure of PDB 7l4f Chain A Binding Site BS02

Receptor Information
>7l4f Chain A (length=350) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIRLPNPMIGFGVPNEPGLITHRSLPELARGPPFFYYENVALTPKGVWET
ISRHLFEIPPEFVDSKYFCVAARKRGYIHNLPINNRFQIQPPPKYTIHDA
FPLSKRWWPEWDKRTKLNCILTCTGSAQLTNRIRVALEPYNEEPEPPKHV
QRYVIDQCKKWNLVWVGKNKAAPLEPDEMESILGFPKNHTRGGGMSRTER
FKSLGNSFQVDTVAYHLSVLKPIFPHGINVLSLFTGIGGGEVALHRLQIK
MKLVVSVEISKVNRNILKDFWEQTNQTGELIEFSDIQHLTNDTIEGLMEK
YGGFDLVIGGSPCNNLAGGNRVSRVGLEGDQSSLFFEYCRILEVVRARMR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l4f Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Resolution2.55 Å
Binding residue
(original residue number in PDB)
E312 V314 R347 R349 N392 T396 C397 N480 C587 N588 G592 R595 V596
Binding residue
(residue number reindexed from 1)
E38 V40 R73 R75 N118 T122 C123 N206 C313 N314 G318 R321 V322
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7l4f, PDBe:7l4f, PDBj:7l4f
PDBsum7l4f
PubMed34078593
UniProtQ9M548|DRM2_ARATH DNA (cytosine-5)-methyltransferase DRM2 (Gene Name=DRM2)

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