Structure of PDB 7l4c Chain A Binding Site BS02

Receptor Information
>7l4c Chain A (length=353) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPIRLPNPMIGFGVPNEPGLITHRSLPELARGPPFFYYENVALTPKGVWE
TISRHLFEIPPEFVDSKYFCVAARKRGYIHNLPINNRFQIQPPPKYTIHD
AFPLSKRWWPEWDKRTKLNCILTCTGSAQLTNRIRVALEPYNEEPEPPKH
VQRYVIDQCKKWNLVWVGKNKAAPLEPDEMESILGFPKNHTRGGGMSRTE
RFKSLGNSFQVDTVAYHLSVLKPIFPHGINVLSLFTGIGGGEVALHRLQI
KMKLVVSVEISKVNRNILKDFWEQTNQTGELIEFSDIQHLTNDTIEGLME
KYGGFDLVIGGSPCNNLAGGNRVSRVGLEGDQSSLFFEYCRILEVVRARM
RGS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l4c Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Resolution2.11 Å
Binding residue
(original residue number in PDB)		E312 V314 K348 R349 N392 C393 L395 T396 C397 G479 N480 G584 S585 P586 C587 N588 G592 G593 N594 R595 V596
Binding residue
(residue number reindexed from 1)		E39 V41 K75 R76 N119 C120 L122 T123 C124 G206 N207 G311 S312 P313 C314 N315 G319 G320 N321 R322 V323
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7l4c, PDBe:7l4c, PDBj:7l4c
PDBsum7l4c
PubMed34078593
UniProtQ9M548|DRM2_ARATH DNA (cytosine-5)-methyltransferase DRM2 (Gene Name=DRM2)

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