Structure of PDB 7kz1 Chain A Binding Site BS02
Receptor Information
>7kz1 Chain A (length=143) Species:
9606
(Homo sapiens) [
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KKWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKY
PSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELH
GIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLS
Ligand information
>7kz1 Chain D (length=12) [
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gctgcgcgctgg
Receptor-Ligand Complex Structure
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PDB
7kz1
Structural Insights into the Mechanism of Base Excision by MBD4.
Resolution
1.62 Å
Binding residue
(original residue number in PDB)
R468 M473 K504 G507 L508 Y509 D510 L511
Binding residue
(residue number reindexed from 1)
R33 M38 K69 G72 L73 Y74 D75 L76
Enzymatic activity
Enzyme Commision number
3.2.2.-
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003824
catalytic activity
Biological Process
GO:0006281
DNA repair
GO:0006284
base-excision repair
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Molecular Function
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Biological Process
External links
PDB
RCSB:7kz1
,
PDBe:7kz1
,
PDBj:7kz1
PDBsum
7kz1
PubMed
34107280
UniProt
O95243
|MBD4_HUMAN Methyl-CpG-binding domain protein 4 (Gene Name=MBD4)
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