Structure of PDB 7kx9 Chain A Binding Site BS02

Receptor Information
>7kx9 Chain A (length=734) Species: 31330 (Ephydatia fluviatilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQRGSSGQPVPVSANYLPLKGNMDGVFKYAVGFNPPVEDIRSRSQLLNEH
KELIGLTRVFDGSTLYVPKRICEQRLDLMSTRQTDGASIKVTISLVDSVK
NRDVVQLMNVIFKRILRSLKLQRIGRDYYDANSPLEVPQHKMQLWPGYVT
AINRHEGGLMLVLDVSHRVMKTDTALDFLYELYHFKQLVGSVVLTRYNNR
TYEIDDIAWDKNPRCAFQDHAGSQITFVDYYKRAYDLDITDLEQPLLIHR
PKEMVCLVPELCAMTGLTDAARSDFKVMKDLAVHTRVPPEKRAESFRKFI
QRLNTTKEASELLHSWGLVLDSRMLDMQGRRLPPEKILFKHSSIVANMEA
DWSRECLKEHVISAVSLLDWAVLFVRKDQGKATDFVNMLSKVCPPIGMEV
HEPKMVEVVNDRTESYLRALRELIAPRLQMVVIVFPTSRDDRYSAVKKLC
CIESPIPSQVLIARTITQQQKLRSVAQKVALQMNAKLGGELWAVEIPLKS
CMVVGIDVYHDKSYGNKSIAGFVASTNPSFTRWYSRTAMQEQSQELIHEL
KLCMQAALKKYNEMNQSLPERIIVFRDGVGEGREEYVSEFEVPQFNSCFS
IFGENYCPKLAVVVVQKRITTRIFGRSGHSYDNPPPGVIVDHTITKSYDF
YLVSQHVRQGTVSPTYYRVIYDKSGLKPDHLQRLTYKLTHMYYNWPGTIR
TPAPCNYAHKLAFLVGKSLHRDPAHELSDRLFFL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7kx9 Structural basis for piRNA targeting.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R351 G353 R354 K490 Q723 K724 S727 K731 H763 R871 F966
Binding residue
(residue number reindexed from 1)
R123 G125 R126 K252 Q470 K471 S474 K478 H510 R618 F713
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7kx9, PDBe:7kx9, PDBj:7kx9
PDBsum7kx9
PubMed34471284
UniProtD5MRY8

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