Structure of PDB 7ktq Chain A Binding Site BS02

Receptor Information
>7ktq Chain A (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Ligand information
>7ktq Chain J (length=167) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tacccgggatatcggatgtatatatctgacacgtgcctggagactaggga
gtaatccccttggcggttaaaacgcgggggacagcgcgtacgtgcgttta
agcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggat
tctcgatatcccgggta
Receptor-Ligand Complex Structure
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PDB7ktq Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
R40 V46 A47 R49 R63 L65 R69
Binding residue
(residue number reindexed from 1)
R4 V10 A11 R13 R27 L29 R33
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7ktq, PDBe:7ktq, PDBj:7ktq
PDBsum7ktq
PubMed33514705
UniProtP84233|H32_XENLA Histone H3.2

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