Structure of PDB 7krv Chain A Binding Site BS02

Receptor Information
>7krv Chain A (length=538) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVG
QPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDA
WVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQR
QATKDAGRIAGLEVKCIINEPTAAALAYGLDKGTGNRTIAVYDLGGGAFD
ISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGID
LRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVT
RAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQK
KVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGI
ETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADN
KSLGQFNLDGINPAPRGMPQIEVTFDIDCDGILHVSAKDKNSGKEQKITI
KASSGLNEDEIQKMVRDAEANAEADRKFEELVRLLLTG
Ligand information
Ligand ID6LN
InChIInChI=1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2
InChIKeyVYMPLPIFKRHAAC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.4C(CS)S
CACTVS 3.385SCCS
ACDLabs 12.01C(S)CS
FormulaC2 H6 S2
Nameethane-1,2-dithiol
ChEMBL
DrugBank
ZINCZINC000059436273
PDB chain7krv Chain A Residue 606 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7krv Conformational equilibria in allosteric control of Hsp70 chaperones.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		C167 C480
Binding residue
(residue number reindexed from 1)		C166 C479
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:7krv, PDBe:7krv, PDBj:7krv
PDBsum7krv
PubMed34453889
UniProtP0A6Y8|DNAK_ECOLI Chaperone protein DnaK (Gene Name=dnaK)

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