Structure of PDB 7kjn Chain A Binding Site BS02
Receptor Information
>7kjn Chain A (length=85) Species:
9606
(Homo sapiens) [
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INQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDAAAQHM
VYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT
Ligand information
>7kjn Chain C (length=12) Species:
32630
(synthetic construct) [
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EFWYVEFEKLLR
Receptor-Ligand Complex Structure
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PDB
7kjn
CRYSTAL STRUCTURE OF HUMAN MDMX IN COMPLEX WITH D-PEPTIDE INHIBITOR (DPMI-OMEGA)
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
I24 N25 V49 K93 D94 P95 Y99 L102 R103 L106
Binding residue
(residue number reindexed from 1)
I1 N2 V26 K70 D71 P72 Y76 L79 R80 L83
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0043066
negative regulation of apoptotic process
GO:0051726
regulation of cell cycle
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:7kjn
,
PDBe:7kjn
,
PDBj:7kjn
PDBsum
7kjn
PubMed
UniProt
O15151
|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)
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