Structure of PDB 7go5 Chain A Binding Site BS02

Receptor Information
>7go5 Chain A (length=182) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGPGFDFAQAIMKKNTVIARTEKGEFTMLGVYDRVAVIPTHASVGEIIYI
NDVETRVLDACALRDLTDTNLEITIVKLDRNQKFRDIRHFLPRCEDDYND
AVLSVHTSKFPNMYIPVGQVTNYGFLNLGGTPTHRILMYNFPTRAGQCGG
VVTTTGKVIGIHVGGNGAQGFAAMLLHSYFTD
Ligand information
Ligand IDTZ9
InChIInChI=1S/C9H6F2O/c10-7-4-6-2-1-3-12-9(6)8(11)5-7/h1-2,4-5H,3H2
InChIKeyDRQKJKGKLYCHHB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7c1c(cc(c2c1C=CCO2)F)F
ACDLabs 12.01
CACTVS 3.385		Fc1cc(F)c2OCC=Cc2c1
FormulaC9 H6 F2 O
Name6,8-bis(fluoranyl)chromene
ChEMBL
DrugBank
ZINCZINC000039941619
PDB chain7go5 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7go5 PanDDA analysis group deposition
Resolution1.5 Å
Binding residue
(original residue number in PDB)		M0 G1
Binding residue
(residue number reindexed from 1)		M1 G2
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7go5, PDBe:7go5, PDBj:7go5
PDBsum7go5
PubMed
UniProtQ68T42|POLG_HED68 Genome polyprotein

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