Structure of PDB 7gat Chain A Binding Site BS02

Receptor Information
>7gat Chain A (length=66) Species: 162425 (Aspergillus nidulans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKNGEQNGPTTCTNCFTQTTPVWRRNPEGQPLCNACGLFLKLHGVVRPLS
LKTDVIKKRNRNSANS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7gat Chain A Residue 67 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7gat The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity.
ResolutionN/A
Binding residue
(original residue number in PDB)		C12 C15 C33 C36
Binding residue
(residue number reindexed from 1)		C12 C15 C33 C36
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:7gat, PDBe:7gat, PDBj:7gat
PDBsum7gat
PubMed9533884
UniProtP17429|AREA_EMENI Nitrogen regulatory protein areA (Gene Name=areA)

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