Structure of PDB 7f19 Chain A Binding Site BS02

Receptor Information
>7f19 Chain A (length=444) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AERPTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAV
KLQRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVT
LNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGI
DDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPR
GWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMG
ERFEVLVEVNDNKPFDLVTLPVSQMEMAIAPFDKPHPVMRIQPIAISASG
ALPDTLSSLPALPSLEGLTVRKLQLSMDPMDFHHANKINGQAFDMNKPMF
AAAKGQYERWVISGVGDMMLHPFHIHGTQFRILSENGKPPAAHRAGWKDT
VKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDTGMMLGFTV
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain7f19 Chain A Residue 607 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7f19 Structure of the G304E mutant of CueO
Resolution1.773 Å
Binding residue
(original residue number in PDB)		H443 C500 H505
Binding residue
(residue number reindexed from 1)		H371 C428 H433
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.4: cuproxidase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:7f19, PDBe:7f19, PDBj:7f19
PDBsum7f19
PubMed
UniProtP36649|CUEO_ECOLI Multicopper oxidase CueO (Gene Name=cueO)

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