Structure of PDB 7ey3 Chain A Binding Site BS02

Receptor Information

>7ey3 Chain A (length=387) Species: 213419 (Geobacillus zalihae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

CLRANDAPIVLLHGFTGWGREEMFGFKYWGGVRGDIEQWLNDNGYRTYTL
AVGPLSSNWDRACEAYAQLVGGTVDYGAAHAAKHGHARFGRTYPGLLPEL
KRGGRIHIIAHSQGGQTARMLVSLLENGSQEEREYAKAHNVSLSPLFEGG
HHFVLSVTTIATPHDGTTLVNMVDFTDRFFDLQKAVLEAAAVASNVPYTS
QVYDFKLDQWGLRRQPGESFDHYFERLKRSPVWTSTDTARYDLSVSGAEK
LNQWVQASPNTYYLSFSTERTYRGALTGNHYPELGMNAFSAVVCAPFLGS
YRNPTLGIDDRWLENDGIVNTVSMNGPKRGSSDRIVPYDGTLKKGVWNDM
GTYNVDHLEIIGVDPNPSFDIRAFYLRLAEQLCSLQP

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

7ey3 Chain A Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7ey3 Double cysteine mutations in T1 lipase
Resolution	2.04 Å
Binding residue (original residue number in PDB)	G286 E360 D365 P366
Binding residue (residue number reindexed from 1)	G285 E359 D364 P365
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.1.3: triacylglycerol lipase.

Gene Ontology

	Molecular Function
GO:0004806	triacylglycerol lipase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0016042	lipid catabolic process

	Cellular Component
GO:0005576	extracellular region

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Cellular Component

External links

PDB	RCSB:7ey3, PDBe:7ey3, PDBj:7ey3
PDBsum	7ey3
PubMed	36752811
UniProt	Q842J9

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