Structure of PDB 7eu9 Chain A Binding Site BS02

Receptor Information
>7eu9 Chain A (length=1078) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NASETRKAYTTKMIPRSHDRMKLLGNFMDYLMDGTPIFFELWNQFGGGID
RDIISGTANKDKISDDLLLAVNWFKVMPINSKPQGVSPSNLANLFQQYSG
SEPDIQAQEYFASNFDTEKHQWKDMRVEYERLLAELQLSRSDMHHDLKLM
YKEKCIGLSLSTAHYITSVMFGTGAKNNRQTKHQFYSKVIQLLEESTQIN
SVEQLASIILKAGDCDSYRKLRIRCSRKGATPSILKIVQDYELGTNHDDE
VNVPSLIANLKEKLGRFEYECEWKCMEKIKAFLASKVGPYYLGSYSAMLE
NALSPIKGMTTKNCKFVLKQIDAKNDIKYENEPFGKIVEGFFDSPYFESD
TNVKWVLHPHHIGESNIKTLWEDLNAIHSKYEEDIASLSEDKKEKRIKVY
QGDVCQTINTYCEEVGKEAKTPLVQLLRYLYSRKDDIAVDKIIDGITFLS
KKHKVEKQKINPVIQKYPSFNFGNNSKLLGKIISPKDKLKHNLKCNRNQV
DNYIWIEIKVLNTKTMRWEKHHYALSSTRFLEEVYYPATSENPPDALAAR
FRTKTNGYEGKPALSAEQIEQIRSAPVGLRKVKKRQMRLEAARQQNLLPR
YTWGKDFNINICKRGNNFEVTLATKVKKKKEKNYKVVLGYAANIVRKNTY
AAIEAHANGDGVIDYNDLPVKPIESGFVTVESQVRDKSYDQLSYNGVKLL
YCKPHVESRRSFLEKYRNGTMKDNRGNNIQIDFMKDFEAIADDETSLYYF
NMKYCKLLQSSIRNHSSQAKEYREEIFELLRDGKLSVLKLSSLSNLSFVM
FKVAKSLIGTYFGHLLKKPKAPPITDEDKQKADPEMFALRLALEEKRLNK
VKSKKEVIANKIVAKALELRDKYGPVLIKGENISDTTKKGKKSSTNSFLM
DWLARGVANKVKEMVMMHQGLEFVEVNPNFTSHQDPFVHKNPENTFRARY
SRCTPSELTEKNRKEILSFLSDKPSKRPTNAYYNEGAMAFLATYGLKKND
VLGVSLEKFKQIMANILHQRSEDQLLFPSRGGMFYLATYKLDADATSVNW
NGKQFWVCNADLVAAYNVGLVDIQKDFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7eu9 Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Resolution2.35 Å
Binding residue
(original residue number in PDB)
R12 T168 R228 R233 K234 G235 A236 S310 K313 G314 T317 K321 W361 H366 H367 K426 T427 L429 N477 N481 S482 K483 N614 K631 K728 T838 D839 R860 M913 L916 R918 G919 N922
Binding residue
(residue number reindexed from 1)
R6 T162 R222 R227 K228 G229 A230 S304 K307 G308 T311 K315 W355 H360 H361 K420 T421 L423 N471 N475 S476 K477 N608 K625 K722 T825 D826 R847 M900 L903 R905 G906 N909
External links