Structure of PDB 7esc Chain A Binding Site BS02

Receptor Information

>7esc Chain A (length=322) Species: 393133 (Listeria monocytogenes 10403S)

KLMDQPYSKTDFLMGTVVTLKIYDKGKEDVLDKGFDRIKDLAAKITTSDS
EKTSEVDKINEQAGKKPVKVSEDVYYLIQEGLKYSENSGGSFDITIGPLT
SLWHIGFSDARKPSQAEIDAVLPLINYKDVKMNDKDQTVYLEKEGMELDL
GAIAKGFITDETLKVFKENKVTTSIIDLGGNIYVQGNNPNGNKWNVGIQD
PFSPRGSVIGKLPESNMSIVTSGIYERYLEVDGKTYHHILDPKTGYPFDN
DIAGVSIVSKKSIDGDGLSTATFSKGIKGGMDYIEQFEGVDAIFISKEKK
VYETSGLKGQFELTDKDFQMDT

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7esc Chain A Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7esc Structural insights into the catalytic and inhibitory mechanisms of the flavin transferase FmnB in Listeria monocytogenes.
• Resolution: 2.201 Å
• Binding residue (original residue number in PDB): A187 D301
• Binding residue (residue number reindexed from 1): A152 D266
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.1.180: FAD:protein FMN transferase.

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016740 transferase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0017013 protein flavinylation

Cellular Component

• GO:0005886 plasma membrane

External links

• PDB: RCSB:7esc, PDBe:7esc, PDBj:7esc
• PDBsum: 7esc
• PubMed: 35281791
• UniProt: A0A0H3GJF7