Structure of PDB 7eev Chain A Binding Site BS02

Receptor Information
>7eev Chain A (length=397) Species: 44752 (Rhodococcus wratislaviensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGALPIHWGAPTASERGPVVGTTTNRAHRNVIGTHSGSYSIYRALAVASG
ALSRHHKADLTDTAPTNIIGPYPQWSQPGKIVSLDPWGATVAEVFAAELA
AGHDIRPSIAVTKAHVILPEVMEAIQKGRLHPDGRFLLPSGAALVTKAAI
EPVWHLPGVAERFHCSETDLRRVLFEETGGMYPELVTRSDLEVFLPPIGG
QTVYIFGDARDLADPGVELTARVHDECNGSDVFGSDICTCRPYLTHAIEE
CIQGAQRGGVGLVAYSRKEGRALGEVTKFLVYNARKRQVGGDTADQYFAR
TECVAGVQDMRFQEMMPDVLHWLGVRKIHRLVSMSNMKYDAITGSGIEVV
ERVDLPADLIPADARVEIDAKMAAGYFTPGAVPDADELAKVKGRELD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7eev Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7eev Structural and biochemical investigation of UTP cyclohydrolase
Resolution2.15 Å
Binding residue
(original residue number in PDB)		C252 C263 C265
Binding residue
(residue number reindexed from 1)		C227 C238 C240
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003935 GTP cyclohydrolase II activity
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009231 riboflavin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7eev, PDBe:7eev, PDBj:7eev
PDBsum7eev
PubMed
UniProtA0A3D9R4E8

[Back to BioLiP]