Structure of PDB 7e8o Chain A Binding Site BS02

Receptor Information
>7e8o Chain A (length=194) Species: 1801956 (Planctomycetes bacterium GWF2_40_8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RDLKEERFVIDTSIFTNTDVYILFGRTPTTALKNFLKLISKLKGTNFYMP
PSIYEELMNFIDSDKIPKDLQIKIFQKPPKKHEMEVPAFLLYELIEDVRH
RIDKGLRVAEQAVRNVIADKEPETITNLRKKYRSALREGIIDSKEDVDLI
LLAKEMDGILVTADTGIMTWADKMGIRFVESRNLRGIINSLIKM
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7e8o Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7e8o Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P.
Resolution2.804 Å
Binding residue
(original residue number in PDB)		R146 I149 D151 D173
Binding residue
(residue number reindexed from 1)		R137 I140 D142 D164
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004526 ribonuclease P activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0001682 tRNA 5'-leader removal
GO:0008033 tRNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:7e8o, PDBe:7e8o, PDBj:7e8o
PDBsum7e8o
PubMed35484139
UniProtA0A1G2XP69

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