Structure of PDB 7dj2 Chain A Binding Site BS02

Receptor Information

>7dj2 Chain A (length=492) Species: 63363 (Aquifex aeolicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

REHWATRLGLILAMAGNAVGLCNFLRFPVQAAENGGGAFMIPYIIAFLLV
GIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVV
AIYYVYIESWTLGFAIKFLVGLVPEPPPNATDPDSILRPFKEFLYSYIGV
PKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFI
LAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFT
LSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVA
FFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLT
SSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMD
FWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRY
ITPAFLAVLLVVWHWTVWITRFYIIGLFLFLTFLVFLAERRR

Ligand information

Ligand ID

InChI

InChI=1S/Na/q+1

InChIKey

FKNQFGJONOIPTF-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Na+]

Formula

Name

SODIUM ION

PDB chain

7dj2 Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7dj2 Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	G20 V23 G24 A351 T354 S355
Binding residue (residue number reindexed from 1)	G16 V19 G20 A347 T350 S351
Annotation score	3

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0035725	sodium ion transmembrane transport

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7dj2, PDBe:7dj2, PDBj:7dj2
PDBsum	7dj2
PubMed	33811858
UniProt	O67854

[Back to BioLiP]