Structure of PDB 7ddz Chain A Binding Site BS02

Receptor Information
>7ddz Chain A (length=437) Species: 882,9606 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADL
LVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALD
RYRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPD
FEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK
NHVAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFE
GFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSW
EYFCGAVDAIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAI
DHYHQRRQKTTKMLVCVVVVFAVCWLPLHAFQLAVDIDSQVLDLKEYKLI
FTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCE
Ligand information
Ligand IDFMN
InChIInChI=1S/C17H21N4O9P/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29)/t11-,12+,14-/m0/s1
InChIKeyFVTCRASFADXXNN-SCRDCRAPSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)O)O)O)O
OpenEye OEToolkits 1.7.6Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)O)O)O)O
ACDLabs 12.01N=2C(=O)NC(=O)C3=Nc1cc(C)c(C)cc1N(C=23)CC(O)C(O)C(O)COP(=O)(O)O
CACTVS 3.385Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[CH](O)[CH](O)[CH](O)CO[P](O)(O)=O)c2cc1C
CACTVS 3.385Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)CO[P](O)(O)=O)c2cc1C
FormulaC17 H21 N4 O9 P
NameFLAVIN MONONUCLEOTIDE;
RIBOFLAVIN MONOPHOSPHATE
ChEMBLCHEMBL1201794
DrugBankDB03247
ZINCZINC000003831425
PDB chain7ddz Chain A Residue 1202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ddz Structural basis for ligand recognition of the neuropeptide Y Y 2 receptor.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S1008 T1009 T1010 N1012 T1013 S1056 T1057 W1058 G1092 D1093 W1096 F1099 C1100
Binding residue
(residue number reindexed from 1)		S212 T213 T214 N216 T217 S260 T261 W262 G296 D297 W300 F303 C304
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0004930 G protein-coupled receptor activity
GO:0009055 electron transfer activity
GO:0010181 FMN binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ddz, PDBe:7ddz, PDBj:7ddz
PDBsum7ddz
PubMed33531491
UniProtP00323|FLAV_NITV2 Flavodoxin (Gene Name=DVU_2680);
P49146|NPY2R_HUMAN Neuropeptide Y receptor type 2 (Gene Name=NPY2R)

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