Structure of PDB 7d8t Chain A Binding Site BS02

Receptor Information
>7d8t Chain A (length=199) Species: 9606,224324 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTIL
KASVDYIRKLQREQQRAKELENRQKKLEHACRHLLLRIQELGIEDFLKVD
LRVAKVLSAERVEGSEKLLKLTLSLGDEERTVVAGIAKYYTPEELVGKKI
VIVANLKPRKIFGIESQGMILAASDGENLSVIVPDRDVKEGAKLSAALE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d8t A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Resolution3.201 Å
Binding residue
(original residue number in PDB)		R310 H316 N317 R324 N349 K350
Binding residue
(residue number reindexed from 1)		R6 H12 N13 R20 N45 K46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004825 methionine-tRNA ligase activity
GO:0005524 ATP binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006431 methionyl-tRNA aminoacylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7d8t, PDBe:7d8t, PDBj:7d8t
PDBsum7d8t
PubMed36588115
UniProtO66738;
O75030

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