Structure of PDB 7c7l Chain A Binding Site BS02

Receptor Information
>7c7l Chain A (length=503) Species: 115547 (uncultured archaeon) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNTITKTLKLRIVRPYNSAEVEKIVADEKNNREKIALKEACSKHLKVTTQ
VERNACLFCKARKLDDKFYQKLRGQFPDAVFWQEISEIFRQLQKQAAEIY
NQSLIELYYEIFIKGKGIANASSVEHYLSDVCYTRAAELFKNAAIASGLR
SKIKSNFRLKELKNMKSGLPTTKSDNFPIPLVKQKGGQYTGFEISNHNSD
FIIKIPFGRWQVKKEIDKYRPWEKFDFEQVQKSPKPISLLLSTQRRKRNK
GWSKDEGTEAEIKKVMNGDYQTSYIEVKRGSKIGEKSAWMLNLSIDVPKI
DKGVDPSIIGGIAVGVKSPLVCAINNAFSRYSISDNDLFHFNKKMFARRR
ILLKKNRHKRAGHGAKNKLKPITILTEKSERFRKKLIERWACEIADFFIK
NKVGTVQMENLESMKRKEDSYFNIRLWPYAEMQNKIEFKLKQYGIEIRKV
APNNTSKTCSKCGHLNNYFNFEYRKKNKFPHFKCEKCNADYNAALNISNP
KLK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7c7l Structure of the miniature type V-F CRISPR-Cas effector enzyme.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		T7 K167 S168 R171 Q197 K198 Y202 S286 L382 L424 K428 W443 P444 Y445 A446
Binding residue
(residue number reindexed from 1)		T5 K154 S155 R158 Q184 K185 Y189 S273 L369 L411 K415 W427 P428 Y429 A430
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7c7l, PDBe:7c7l, PDBj:7c7l
PDBsum7c7l
PubMed33333018
UniProtA0A482D308|CS12F_UNCAX CRISPR-associated endodeoxyribonuclease Cas12f1 (Gene Name=cas12f)

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