Structure of PDB 7c3l Chain A Binding Site BS02

Receptor Information
>7c3l Chain A (length=505) Species: 5547 (Trichoderma viride) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELPPRKVCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHH
FTDAKHDYYDIGAMRYPDIPSMKRTFNLFKRTGMPLIKYYLDGENTPQLY
NNHFFAKGVVDPYMVSVANGGTVPDDVVDSVGEKLQQAFGYYKEKLAEDF
DKGFDELMLVDDMTTREYLKRGGPKGEAPKYDFFAIQWMETQNTGTNLFD
QAFSESVIASFDFDNPTKPEWYCIEGGTSLLVDAMKETLVHKVQNNKRVE
AISIDLDAPDDGNMSVKIGGKDYSGYSTVFNTTALGCLDRMDLRGLNLHP
TQADAIRCLHYANSTKVALKFSYPWWIKDCGITCGGAASTDLPLRTCVYP
SYNLGDTGEAVLLASYTWSQDATRIGSLVKDAPPQPEDELVELILQNLAR
LHAEHMTYEKIKEAYTGVYHAYCWANDPNVGGAFALFGPGQFSNLYPYLM
RPAAGGKFHIVGEASSVHHAWIIGSLESAYTAVYQFLYKYKMWDYLRLLL
ERWQY
Ligand information
Ligand IDTYR
InChIInChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
InChIKeyOUYCCCASQSFEME-QMMMGPOBSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(N)Cc1ccc(O)cc1
OpenEye OEToolkits 1.5.0c1cc(ccc1C[C@@H](C(=O)O)N)O
OpenEye OEToolkits 1.5.0c1cc(ccc1CC(C(=O)O)N)O
CACTVS 3.341N[CH](Cc1ccc(O)cc1)C(O)=O
CACTVS 3.341N[C@@H](Cc1ccc(O)cc1)C(O)=O
FormulaC9 H11 N O3
NameTYROSINE
ChEMBLCHEMBL925
DrugBankDB00135
ZINCZINC000000266964
PDB chain7c3l Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7c3l Structural basis of strict substrate recognition of l-lysine alpha-oxidase from Trichoderma viride.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		R68 F216 Y369 W371 F439 A475 W476
Binding residue
(residue number reindexed from 1)		R65 F213 Y366 W368 F434 A470 W471
Annotation score2
Enzymatic activity
Enzyme Commision number 1.4.3.14: L-lysine oxidase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:7c3l, PDBe:7c3l, PDBj:7c3l
PDBsum7c3l
PubMed32894626
UniProtA0A0G4DCU0

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