Structure of PDB 7bfi Chain A Binding Site BS02

Receptor Information

>7bfi Chain A (length=372) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KLSPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLG
GKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRL
YGPSSVSFAEDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGK
LPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGV
TMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPNNVEPLERLEKL
LTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNK
ADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDELRSPKLFYADHPFIFL
VRDTQSGSLLFIGRLVRPKGDK

Ligand information

>7bfi Chain E (length=14) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PPGPPGPRGPPGPP

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7bfi Collagen's primary structure determines collagen:HSP47 complex stoichiometry.
Resolution	2.44 Å
Binding residue (original residue number in PDB)	M218 R222 L381 D385 H386
Binding residue (residue number reindexed from 1)	M184 R188 L340 D344 H345

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005518	collagen binding

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005783	endoplasmic reticulum

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7bfi, PDBe:7bfi, PDBj:7bfi
PDBsum	7bfi
PubMed	34487762
UniProt	A0A8I3N7V2

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