Structure of PDB 7b19 Chain A Binding Site BS02

Receptor Information
>7b19 Chain A (length=750) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECG
EIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEP
AVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNE
VAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVA
GRVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGAS
IQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYL
NQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNI
KFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQ
HLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISG
FEIFKVNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFG
LDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAK
YEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNV
VTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLEGGGNPHFVRCI
IPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYN
VPRDAEDSQKATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEAREQR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7b19 Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7b19 Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		T186 S237
Binding residue
(residue number reindexed from 1)		T186 S230
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7b19, PDBe:7b19, PDBj:7b19
PDBsum7b19
PubMed33374308
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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