Structure of PDB 7aoh Chain A Binding Site BS02

Receptor Information
>7aoh Chain A (length=1263) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVISKVTYSLYDQKEINATDIIISHVKNDDDIGTVKDGRLGAMDGALCKT
CGKTELECFGHWGKVSIYKTHIVKPEFISEIIRLLNHICIHCGLLRSREP
YSDDINLKELSGHALRRLKDKILSKKKSCWNSECMQPYQKITFSKKKVCF
VNKLDDINVPNSLIYQKLISIHEKFWPLLEIHQYPANLFYTDYFPIPPLI
IRPAISFWIDSIPKETNELTYLLGMIVKNCNLNADEQVIQKAVIEYDDIK
IISNNTTSINLSYITSGKNNMIRSYIVARRKDQTARSVIGPSTSITVNEV
GMPAYIRNTLTEKIFVNAFTVDKVKQLLASNQVKFYFNKRLNQLTRIRQG
KFIKNKIHLLPGDWVEVAVQEYTSIIFGRQPSLHRYNVIASSIRATEGDT
IKISPGIANSQNADFDGDEEWMILEQNPKAVIEQSILMYPTTLLKHDIHG
APVYGSIQDEIVAAYSLFRIQDLCLDEVLNILGKYGREFDPKGKCKFSGK
DIYTYLIGEKINYPGLLKDGEIIANDVDSNFVVAMRHLSLAGLLSDHKSN
VEGINFIIKSSYVFKRYLSIYGFGVTFKDLRPNSTFTNKLEAINVEKIEL
IKEAYAKYLNDVRDGKIVPLSKALEADYVESMLSNLTNLNIREIEEHMRQ
TLIDDPDNNLLKMAKAGYKVNPTELMYILGTYGQQRIDGEPAETRVLGRV
LPYYLPDSKDPEGRGYILNSLTKGLTGSQYYFSMLVARSQSTDIVCETSR
TGTLARKIIKKMEDMVVDGYGQVVIGNTLIKYAANYTKILGSVCKPVDLI
YPDESMTWYLEISALWNKIKQGFVYSQKQKLAKKTLAPFNFLVFVKPTTE
DNAIKVKDLYDMIHNVIDDVREKYFFTVSNIDFMEYIFLTHLNPSRIRIT
KETAITIFEKFYEKLNYTLGGGTPIGIISAQVLSEKFTQQALSSFHTTEK
SGAVKQKLGFNEFNNLTNLSKNKTEIITLVSDDISKLQSVKINFEFVCLG
ELNPNITLRKETDKYVVDIIVNRLYIKRAEITELVVEYMIERFISFSVIV
KEWGMETFIEDEDNIRFTVYLNFVEPEELNLSKFMMVLPGAANKGKISKF
KIPISDYTGYDDFNQTKKLNKMTVELMNLKELGSFDLENVNVYPGVWNTY
DIFGIEAAREYLCEAMLNTYGEGFDYLYQPCDLLASLLCASYEPESVNKF
KFGAASTLKRATFGDNKALLNAALHKKSEPINDNSSCHFFSKVPNIGTGY
YKYFIDLGLLMRM
Ligand information
Receptor-Ligand Complex Structure
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PDB7aoh Structural basis of the complete poxvirus transcription initiation process.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		K269 R281 R287 Q381 T749 S750
Binding residue
(residue number reindexed from 1)		K268 R280 R286 Q380 T748 S749
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aoh, PDBe:7aoh, PDBj:7aoh
PDBsum7aoh
PubMed34556871
UniProtQ1PIV1

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