Structure of PDB 7aar Chain A Binding Site BS02

Receptor Information
>7aar Chain A (length=485) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVES
QMKKAKHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSM
FIGGLAFLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSQMAP
AKIRGALNIGFQMAITIGILVANLINYGTSKMAQHGWRVSLGLAAVPAVV
MVIGSFILPDTPNSMLERGKNEEAKQMLKKIRGADNVDHEFQDLIDAVEA
AKKVENPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPVLFKTLG
FGDDAALMSAVITGVVNMLSTFVSIYAVNRYGRRLLFLEGGIQMFICQLL
VGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSE
ICPLEIRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAI
MTVFIYFLLPETKGVPIEEMGRVWKQHWFWKKYIP
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain7aar Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7aar Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10.
Resolution2.64 Å
Binding residue
(original residue number in PDB)		Q295 N301 M304 G406 W410
Binding residue
(residue number reindexed from 1)		Q280 N286 M289 G391 W395
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005354 galactose transmembrane transporter activity
GO:0009679 hexose:proton symporter activity
GO:0015144 carbohydrate transmembrane transporter activity
GO:0015145 monosaccharide transmembrane transporter activity
GO:0015293 symporter activity
GO:0015578 mannose transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0008645 hexose transmembrane transport
GO:0015749 monosaccharide transmembrane transport
GO:0015757 galactose transmembrane transport
GO:0015761 mannose transmembrane transport
GO:0055085 transmembrane transport
GO:0071333 cellular response to glucose stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aar, PDBe:7aar, PDBj:7aar
PDBsum7aar
PubMed34556835
UniProtQ9LT15|STP10_ARATH Sugar transport protein 10 (Gene Name=STP10)

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