Structure of PDB 6yuf Chain A Binding Site BS02

Receptor Information
>6yuf Chain A (length=384) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRLLRLEVENFKSYRGHQIIGPFEDFTSIIGPNGAGKSNLMDAISFVLGV
KSSHLRSTNVKELIPTTAYVKLMYELDNGEQREYKRAITPSGATEYKIDE
EIVTFSEYCGSLQKENILVRARNFLVFQGDVETIASQSPLELSKLVEQIS
GSLEYKSEYDKSKDEQDKAVNLSAHSFNKKRGINAELRLETVETRLAKLD
EEFAAARKAAKNAKERFNAVKQKRLQKFQAAFSHISEQIDPIYKELTKSP
AFPLGGTAYLTLDDLDEPYLGGIKFHAMPPMKRFRDMDQLSGGEKTMAAL
ALLFAIHSYQPSPFFVLDEIDAALDQTNVTKIANYIRQHASSGFQFVVIS
LKNQLFSKSEALVGIYRDQQENSSRTLSINLEGY
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain6yuf Chain A Residue 1301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6yuf A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Resolution3.94 Å
Binding residue
(original residue number in PDB)		K38 S39 R57 Q147 D1160
Binding residue
(residue number reindexed from 1)		K37 S38 R56 Q128 D318
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0061776 topological DNA co-entrapment activity
Biological Process
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0140588 chromatin looping
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0008278 cohesin complex
GO:0030892 mitotic cohesin complex
GO:0030893 meiotic cohesin complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6yuf, PDBe:6yuf, PDBj:6yuf
PDBsum6yuf
PubMed32755595
UniProtO94383|SMC1_SCHPO Structural maintenance of chromosomes protein 1 (Gene Name=psm1)

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