Structure of PDB 6ymv Chain A Binding Site BS02

Receptor Information
>6ymv Chain A (length=887) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INFFEIYNSLPTLEEKKAFESALNIFNQDRQKVLENRATEAARERWKHDF
EEAKARGDISIEKNLNVKLWKWYNEMLPLVKEEINHCRSLLSEKLSDKKG
LNKVDTNRLGYGPYLTLIDPGKMCVITILELLKLNSTGGVIEGMRTARAV
ISVGKAIEMEFRSEQVLKSESQAKILWPQSIRARIGSVLISMLIQVAKVS
VQGVDPVTKAKVHGEAPAFAHGYQYHNGSKLGVLKIHKTLIRQLNGERLI
ASVQPQLLPMLVEPKPWVNWRSGGYHYTQSTLLRTKDSPEQVAYLKAASD
NGDIDRVYDGLNVLGRTPWTVNRKVFDVVSQVWNKGEGFLDIPGAQDEMV
LPPAPPKNSDPSILRAWKLQVKTIANKFSSDRSNRCDTNYKLEIARAFLG
EKLYFPHNLDFRGRAYPLSPHFNHLGNDMSRGLLIFWHGKKLGPSGLKWL
KIHLSNLFGFDKLPLKDRVAFTESHLQDIKDSAENPLTGDRWWTTADKPW
QALATCFELNEVMKMDNPEEFISHQPVHQDGTCNGLQHYAALGGDVEGAT
QVNLVPSDKPQDVYAHVARLVQKRLEIAAEKGDENAKILKDKITRKVVKQ
TVMTNVYGFSKYLTKHVFSAIRELFHSAHLIQDWLGESAKRISKSIRLDV
DEKSFKNGNKPDFMSSVIWTTPLGLPIVQPYREESKKQVETNLQTVFISD
PFAVNPVNARRQKAGLPPNFIHSLDASHMLLSAAECGKQGLDFASVHDSY
WTHASDIDTMNVVLREQFIKLHEVDLVLRLKEEFDQRYKNYVKIGKLKRS
TDLAQKIIRIRKDLSRKLGRSTTLADEIYFEKKRQELLNEDITDLDALEL
ENGNSGMSVLLPLRLPEIPPKGDFDVTVLRNSQYFFS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ymv Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		Y638 S644 K645 L646 G647 Q1129 Q1135 T1136 V1137 F1138 R1151
Binding residue
(residue number reindexed from 1)		Y223 S229 K230 L231 G232 Q688 Q694 T695 V696 F697 R710
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001018 mitochondrial promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003896 DNA primase activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0000002 mitochondrial genome maintenance
GO:0006269 DNA replication, synthesis of primer
GO:0006351 DNA-templated transcription
GO:0006390 mitochondrial transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0034245 mitochondrial DNA-directed RNA polymerase complex
GO:0042645 mitochondrial nucleoid
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ymv, PDBe:6ymv, PDBj:6ymv
PDBsum6ymv
PubMed33278362
UniProtP13433|RPOM_YEAST DNA-directed RNA polymerase, mitochondrial (Gene Name=RPO41)

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