Structure of PDB 6y5d Chain A Binding Site BS02

Receptor Information
>6y5d Chain A (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVGLFEDTNLAAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6y5d Chain J (length=153) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcacaggatgtatatatctgacacgtgcctggagactagggagtaatcc
ccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtg
ctagagctgtctacgaccaattgagcggcctcggcaccgggattctccag
gat
Receptor-Ligand Complex Structure
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PDB6y5d Structural mechanism of cGAS inhibition by the nucleosome.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		R41 Y42 P44 G45 V47 R64 K65 R70
Binding residue
(residue number reindexed from 1)		R3 Y4 P6 G7 V9 R26 K27 R32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6y5d, PDBe:6y5d, PDBj:6y5d
PDBsum6y5d
PubMed32911482
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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