Structure of PDB 6y35 Chain A Binding Site BS02

Receptor Information

>6y35 Chain A (length=53) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

YVNAKQFHRILKRRVARQKLEEQLRLRKPYLHESRHNHAMRRPRGPGGRF
LTA

Ligand information

>6y35 Chain E (length=25) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aaacccgccaatcagatgcatgatg

Receptor-Ligand Complex Structure

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PDB	6y35 Structural basis of HapE P88L -linked antifungal triazole resistance in Aspergillus fumigatus .
Resolution	2.6 Å
Binding residue (original residue number in PDB)	H269 S271 R272 H275 R279 R286 F287 T289
Binding residue (residue number reindexed from 1)	H32 S34 R35 H38 R42 R49 F50 T52

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:6y35, PDBe:6y35, PDBj:6y35
PDBsum	6y35
PubMed	32467317
UniProt	Q4X049

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