Structure of PDB 6xtq Chain A Binding Site BS02

Receptor Information

>6xtq Chain A (length=302) Species: 471852 (Thermomonospora curvata DSM 43183) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MPSFDFDIPRRSPQEIAKGMVAIPGGTFRMGGEDPDAFPEDGEGPVRTVR
LSPFLIDRYAVSNRQFAAFVKATGYVTDAERYGWSFVFHAHVAPGTPVMD
AVVPEAPWWVAVPGAYWKAPEGPGSSITDRPNHPVVHVSWNDAVAYATWA
GKRLPTEAEWEMAARGGLDQARYPWGNELTPRGRHRCNIWQGTFPVHDTG
EDGYTGTAPVNAFAPNGYGLYNVAGNVWEWCADWWSADWHATESPATRID
PRGPETGTARVTKGGSFLCHESYCNRYRVAARTCNTPDSSAAHTGFRCAA
DP

Ligand information

InChI=1S/Cu/q+1

VMQMZMRVKUZKQL-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Cu+]

Formula

Name

COPPER (I) ION

ChEMBL

DrugBank

ZINC

PDB chain

6xtq Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6xtq Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Resolution	1.4 Å
Binding residue (original residue number in PDB)	C269 C274
Binding residue (residue number reindexed from 1)	C269 C274
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.8.3.7: formylglycine-generating enzyme.

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0120147	formylglycine-generating oxidase activity
GO:1903136	cuprous ion binding

	Biological Process
GO:0018158	protein oxidation
GO:0043687	post-translational protein modification

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Molecular Function

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Biological Process

External links

PDB	RCSB:6xtq, PDBe:6xtq, PDBj:6xtq
PDBsum	6xtq
PubMed
UniProt	D1A7C3\|FGE_THECD Formylglycine-generating enzyme (Gene Name=Tcur_4811)

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