Structure of PDB 6wib Chain A Binding Site BS02

Receptor Information
>6wib Chain A (length=210) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEV
HNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEK
TISKAKGQPREPQVYTFPPSQEEMTKNQVSLRCLVKGFYPSDIAVEWESN
GQPENNYKTTKPVLDSDGSFRLESRLTVDKSRWQEGNVFSCSVMHEACSW
HLCKSLSLSL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6wib Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wib In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Resolution2.55 Å
Binding residue
(original residue number in PDB)
H310 H435
Binding residue
(residue number reindexed from 1)
H76 H201
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6wib, PDBe:6wib, PDBj:6wib
PDBsum6wib
PubMed34497355
UniProtP01861|IGHG4_HUMAN Immunoglobulin heavy constant gamma 4 (Gene Name=IGHG4)

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