Structure of PDB 6w12 Chain A Binding Site BS02

Receptor Information

>6w12 Chain A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQ
KYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGG
EDCAHFHPDGRWNDDVCQRPYHWVCEAGL

Ligand information

InChI=1S/Ca/q+2

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Ca

Name

CALCIUM ION

PDB chain

6w12 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	6w12 Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.
Resolution	2.0 Å
Binding residue (original residue number in PDB)	V218 N220 E224 E305
Binding residue (residue number reindexed from 1)	V39 N41 E45 E126
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:6w12, PDBe:6w12, PDBj:6w12
PDBsum	6w12
PubMed	33724805
UniProt	Q8IUN9\|CLC10_HUMAN C-type lectin domain family 10 member A (Gene Name=CLEC10A)

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