Structure of PDB 6vf1 Chain A Binding Site BS02
Receptor Information
>6vf1 Chain A (length=331) Species:
9606
(Homo sapiens) [
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WMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVL
KALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQT
MKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDL
STPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLIT
HPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSAFERSFCIFRLPQPGSWK
AVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFD
PEQKTFFQAASEEDIFRHLGLEYLPPEQRNA
Ligand information
>6vf1 Chain P (length=5) [
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cgtag
Receptor-Ligand Complex Structure
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PDB
6vf1
DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mg2+ (120 min)
Resolution
1.68 Å
Binding residue
(original residue number in PDB)
G245 V246 G247 T250 D330 D332 F389 R416 D418 G433 W434 G436 K438
Binding residue
(residue number reindexed from 1)
G109 V110 G111 T114 D194 D196 F238 R253 D255 G270 W271 G273 K275
Enzymatic activity
Enzyme Commision number
2.7.7.7
: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003887
DNA-directed DNA polymerase activity
GO:0016779
nucleotidyltransferase activity
GO:0034061
DNA polymerase activity
Biological Process
GO:0006281
DNA repair
Cellular Component
GO:0005634
nucleus
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Molecular Function
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Cellular Component
External links
PDB
RCSB:6vf1
,
PDBe:6vf1
,
PDBj:6vf1
PDBsum
6vf1
PubMed
UniProt
Q9NP87
|DPOLM_HUMAN DNA-directed DNA/RNA polymerase mu (Gene Name=POLM)
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