Structure of PDB 6v73 Chain A Binding Site BS02

Receptor Information
>6v73 Chain A (length=228) Species: 314225 (Erythrobacter litoralis HTCC2594) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DIIRFGEVSFSQLAEGVWMHTTYLDLMGFGPIPSNGLLVVNGDNTILVDT
AWTDEQTEQIVAWASMVLAKPVRAAVVTHAHQDKMGGMAALHGANIATWA
HPLSNELAPEEGLVPARNAITFDANGWATGEAAQSLAPLRLYYPGGAHTR
DNITVGLPELGIAFGGCMIKAGDASNLGNLADADTAAYAQSVRNFAAAFP
DARTIAMSHSPPEGRKAIERTLDLAEEL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6v73 Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6v73 Crystal Structure of Metallo Beta Lactamase from Erythrobacter litoralis with beta mercaptoethanol in the active site
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D116 C200 H242
Binding residue
(residue number reindexed from 1)		D83 C167 H209
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H112 H114 D116 H181 C200 K203 N212 H242
Catalytic site (residue number reindexed from 1) H79 H81 D83 H148 C167 K170 N179 H209
Enzyme Commision number 3.5.2.6: beta-lactamase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6v73, PDBe:6v73, PDBj:6v73
PDBsum6v73
PubMed
UniProtQ2N9N3

[Back to BioLiP]