Structure of PDB 6v3k Chain A Binding Site BS02
Receptor Information
>6v3k Chain A (length=259) Species:
11698,273057
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FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAM
HGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYF
LLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGV
IESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERI
VDIIATDIQTKELQKQITKIQNFRVYYGPAKLLWKGEGAVVIQDNSDIKV
VPRRKAKII
Ligand information
>6v3k Chain F (length=17) [
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cgggaaaatctctagca
Receptor-Ligand Complex Structure
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PDB
6v3k
Structural basis for strand-transfer inhibitor binding to HIV intasomes.
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
E152 K156
Binding residue
(residue number reindexed from 1)
E152 K156
Enzymatic activity
Enzyme Commision number
?
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2
: exoribonuclease H.
3.1.26.13
: retroviral ribonuclease H.
3.4.23.16
: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0003677
DNA binding
GO:0004521
RNA endonuclease activity
GO:0008270
zinc ion binding
Biological Process
GO:0015074
DNA integration
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:6v3k
,
PDBe:6v3k
,
PDBj:6v3k
PDBsum
6v3k
PubMed
32001521
UniProt
P12497
|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol);
P39476
|DN7D_SACS2 DNA-binding protein 7d (Gene Name=sso7d)
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