Structure of PDB 6uei Chain A Binding Site BS02

Receptor Information
>6uei Chain A (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVL
ETITRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYLCKYSHEVL
SEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICN
QQCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNI
QDICNSKHMQK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6uei Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6uei Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences.
Resolution2.51 Å
Binding residue
(original residue number in PDB)		C88 C96 C106 H110
Binding residue
(residue number reindexed from 1)		C81 C89 C93 H97
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6uei, PDBe:6uei, PDBj:6uei
PDBsum6uei
PubMed31719195
UniProtQ7Z2W4|ZCCHV_HUMAN Zinc finger CCCH-type antiviral protein 1 (Gene Name=ZC3HAV1)

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